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Dentro de las enfermedades de la unión neuromuscular, la miastenia grave es una enfermedad de naturaleza autoinmune con predisposición genética, cuyo mecanismo patogénico es la destrucción de los receptores de acetilcolina de la membrana postsináptica de la placa motora por parte de anticuerpos fijadores de complemento.
Se caracteriza por la aparición de debilidad muscular tras una actividad prolongada, con tendencia a la recuperación después de un período de inactividad o la administración de fármacos anticolinesterásicos. Aunque la primera descripción de la enfermedad data de 1672, su relación con una afección del timo no se estableció hasta 1901.
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Villalobos Medina, Mariana Celeste; Jiménez Matute, Jesús Miguel; jmjma1@hotmail.com(Facultad de Odontología, Universidad Central de Venezuela, Caracas, VenezuelaExternoCiencia Inclusiva, 2019-04)
Introduction: Lateral Periodontal Cyst (CPL), also called botrioid odontogenic cyst, is considered an uncommon odontogenic cyst of development, with a higher occurrence between the fifth and seventh decade, predominantly among males. This lesion is generally asymptomatic and radiologically presents as a radiolucent image with well-defined round or oval borders. Case report: In this article, we refer to a clinical case, supported by literature review, of a localized lesion between the lateral incisor and the right lower canine in a male patient of 37 years. A panoramic and periapical radiograph was performed, because the clinical exam presented a whitish lesion at the level of the buccal vestibule in the right anteroinferior area, approximately 8 mm in diameter, soft to palpation of the sessile base. Radiographically, a radiolucent image located laterally between 42 and 43 was detected. The lesion was surgically removed in its entirety without the subsequent application of bone regenerating material; an excisional biopsy of the lesion was performed and the presumptive diagnosis was corroborated. Conclusion: the elimination of the lesion in a single surgical time was a satisfactory treatment for this type of pathologies.
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